DEXLEVO Technology

History of CESABP technology

CESABP(Collagenesis-Enabled Solubilized Active and Biodegradable Polymer) Technology

Many hyaluronic acid products have come out in the market recently, however, they have a big disadvantage that hyaluronic acid is absorbed in the body, and the effects after the application easily disappear within a week or in a few weeks. 

There are some products that make hyaluronic acid maintain longer before the absorption by cross-linking hyaluronic acids using BDDE.

But toxic problems regarding this ingredient are reported.

To solve this problem, some biocompatible and biodegradable polymer products were developed that contain micro-sized particle dispersed in the viscid media. 

Two types of polymer products are commonly used; the particles of 20 to 50um poly lactic acid(PLA) is dispersed in a liquid and another one is that the particles of 20-50um polycaprolactone(PCL) is  dispersed in carboxymethylcellulose(CMS) and glycerin liquid.

But they have an issue that microparticles are sometimes stuck in the needle and it shows effect to the localized part since it does not spread to the entire face.

Dexlevo developed a new type of biocompatible and biodegradable solubilized PCL that smoothly spreads into the entire skin and makes an extensive 3D mesh matrix which lasts up for a long time without inducing phagocytosis.

This CESABP(Collagenesis-Enabled Solubilized Active and Biodegradable Polymer) Technology is Dexlevo’s patented and world’s unique technology that enables regeneration of natural skin collagen without containing microparticles.

And this is an innovation for fundamental Anti-aging.

World’s unique technology of manufacturing of Solubilized PCL for natural skin collagen synthesis

Patent no.(KR) : 10-2018-0058947
Patent no.(US) : 16/410,611
Patent no.(PCT) : PCT/KR2018/005988